Medical Weight Loss

GLP-1 Weight Loss Programmes

Evidence-based, medically supervised weight loss — addressing the metabolic root causes that make weight so hard to shift.

Weight loss rooted in biology — because sustainable change requires more than willpower

A Medical Approach

Weight Loss That Actually Works

Sustainable weight loss isn't about willpower — it's about biology. Hormonal imbalances, insulin resistance, gut dysbiosis, metabolic dysfunction, and chronic inflammation can all make it extremely difficult to lose weight, no matter how hard you try.

At KOI Wellbeing Sorrento Valley, our weight loss programmes start with comprehensive metabolic and hormonal lab testing to understand exactly what's driving your weight gain. We then build a fully personalised programme that may include GLP-1 medications, dietary changes, hormone balancing, IV therapy support, and lifestyle coaching.

This is medicine that addresses the root cause — not a diet plan that masks it.

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GLP-1 Medications

How GLP-1 Therapy Works

GLP-1 (Glucagon-Like Peptide-1) receptor agonists are a class of medications that mimic a natural hormone your gut releases after eating. They slow gastric emptying, reduce appetite, lower blood sugar levels, and signal to your brain that you're full — making it significantly easier to eat less without hunger dominating your life.

Appetite Regulation

Significantly reduces hunger and food cravings, making caloric restriction sustainable rather than a constant struggle.

Blood Sugar Balance

Improves insulin sensitivity and stabilises blood sugar, addressing a core driver of weight gain and metabolic dysfunction.

Metabolic Benefits

Beyond weight loss, GLP-1 medications improve cardiovascular markers, reduce inflammation, and support long-term metabolic health.

Clinically Supervised

All GLP-1 prescriptions at KOI are preceded by lab testing and ongoing clinical monitoring for safety and effectiveness.

Our Primary GLP-1

Semaglutide Programme

Semaglutide (the active ingredient in Wegovy and Ozempic) is currently the most effective GLP-1 medication available for weight loss. Clinical trials show average body weight reductions of 15–20% over 68 weeks when combined with lifestyle intervention.

At KOI Wellbeing Sorrento Valley, our Semaglutide programme is medically supervised from start to finish. We begin with a full metabolic and hormonal panel, establish your starting dose, and gradually titrate upwards to minimise side effects while maximising results.

What's Included

  • Comprehensive metabolic and hormonal lab panel
  • Initial consultation and weight loss goal-setting
  • Weekly Semaglutide injections (self-administered at home)
  • Monthly check-ins and progress monitoring
  • Dietary and nutritional guidance
  • Optional IV and injection support to prevent nutrient depletion
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Dual GIP/GLP-1 Agonist

Tirzepatide Programme

Tirzepatide (the active ingredient in Mounjaro and Zepbound) is the newest and most powerful GLP-1-class medication available. Unlike Semaglutide, which targets only GLP-1 receptors, Tirzepatide is a dual agonist — it also activates GIP (Glucose-dependent Insulinotropic Polypeptide) receptors, amplifying its weight loss effect significantly.

Clinical trials show average body weight reductions of up to 22.5% — making Tirzepatide the most effective non-surgical weight loss treatment ever studied. For patients who haven't responded fully to Semaglutide, or who are looking for maximum impact, Tirzepatide may be the right choice.

Up to 22.5% Weight Loss

The highest average reduction of any studied weight loss medication.

Dual Hormone Action

Targets both GLP-1 and GIP receptors for a stronger metabolic effect.

Weekly Injection

Once-weekly self-injection, gradually titrated to your optimal dose.

Fully Supervised

Full lab panel, clinical monitoring and ongoing support throughout.

Start Your Tirzepatide Programme
15–20%
Average Body Weight Reduction
68
Week Clinical Trial Duration
100%
Medically Supervised
10+
Years of KOI Clinical Experience
More Than Medication

Comprehensive Weight Loss Support

GLP-1 medications are most effective when combined with our full-spectrum support programme. We don't just write prescriptions — we walk the journey with you.

Hormone Optimisation

Thyroid and sex hormone imbalances are common hidden drivers of weight gain — we test and treat both.

IV & Injection Support

Lipotropic injections and IV therapy to boost metabolism and prevent nutrient depletion during weight loss.

Nutritional Guidance

Personalised dietary recommendations that complement your medication and accelerate your results.

Ongoing Monitoring

Regular lab panels, weigh-ins, and clinical check-ins to track progress and fine-tune your programme.

A KOI Differentiator

Nutrition Counselling with a Registered Dietitian

Medication alone is not a complete weight loss strategy. What you eat, when you eat, and how your body processes food are all critical pieces of the puzzle — and they're deeply individual. That's why KOI Wellbeing Sorrento Valley is proud to offer personalised nutrition counselling with Heather McCracken-Cohen, a Registered Dietitian and Board-Certified Nurse Practitioner.

Heather works with you to develop a sustainable, realistic eating plan that complements your GLP-1 therapy, supports your hormonal health, and fits your lifestyle — without restrictive crash dieting. This isn't generic nutrition advice. It's clinical-grade guidance, rooted in your labs, your body, and your goals.

  • Individualised nutrition assessment and planning
  • Protein optimisation during GLP-1 therapy (critical to preserving muscle mass)
  • Blood sugar stabilisation through food timing and composition
  • Gut health and microbiome support through dietary choices
  • Managing side effects of GLP-1 medications through nutrition
  • Long-term maintenance planning after medication taper
Heather McCracken-Cohen, RD, NP-BC Registered Dietitian · Board-Certified Nurse Practitioner
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Ready to Change Your Relationship with Your Body?

Start Your Weight Loss Journey Today

We'll tell you honestly whether our programme is right for you — starting with a comprehensive consultation and metabolic assessment.

Book a Consultation 858-345-1055